doi: 10.1016/0306-3623(82)90114-8.
Flurazepam effects on rat cerebellar Purkinje cells
- PMID: 7173600
- DOI: 10.1016/0306-3623(82)90114-8
Item in Clipboard
Flurazepam effects on rat cerebellar Purkinje cells
Gen Pharmacol.
1982.
Abstract
1. Cerebellar Purkinje cell activity was recorded in urethane anaesthetized rats. 2. Flurazepam, infused intravenously in divided doses totalling 4 mg/kg, decreased simple spike activity, increased complex spike activity and prolonged local surface inhibition. 3. Iontophoretically applied flurazepam enhanced the effect of GABA and elicited a bursting pattern of discharge when released using larger currents for ejection.
Similar articles
-
Comparison of norepinephrine- and benzodiazepine-induced augmentation of Purkinje cell responses to gamma-aminobutyric acid (GABA).J Pharmacol Exp Ther. 1984 Feb;228(2):257-67. J Pharmacol Exp Ther. 1984. PMID: 6319673
-
A presynaptic component of the action of iontophoretically applied flurazepam on feline cortical neurones.Can J Physiol Pharmacol. 1978 Oct;56(5):889-92. doi: 10.1139/y78-140. Can J Physiol Pharmacol. 1978. PMID: 30528
-
A comparison of the effects of flurazepam on gamma-aminobutyric acid mediated depression of cerebellar and cerebral cortical neurons.Can J Physiol Pharmacol. 1981 Jun;59(6):595-8. doi: 10.1139/y81-089. Can J Physiol Pharmacol. 1981. PMID: 7296372
-
Effects of systemic and local ethanol on responses of rat cerebellar Purkinje neurons to iontophoretically applied gamma-aminobutyric acid.Brain Res. 1995 Jul 31;687(1-2):1-11. doi: 10.1016/0006-8993(95)00285-x. Brain Res. 1995. PMID: 7583293
-
The physiological effects of peptides and serotonin on Purkinje cell activity.Prog Neurobiol. 1992 Nov;39(5):475-92. doi: 10.1016/0301-0082(92)90002-v. Prog Neurobiol. 1992. PMID: 1529101 Review. No abstract available.
Cited by
-
Drug-induced rhythmic burst activity of cerebellar neurons.Naunyn Schmiedebergs Arch Pharmacol. 1984 Jun;326(3):227-32. doi: 10.1007/BF00505323. Naunyn Schmiedebergs Arch Pharmacol. 1984. PMID: 6472497
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
