Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982;61(3):264-6.
doi: 10.1007/BF00296457.

Deletion of 13q in two patients with retinoblastoma, one probably due to 13q-mosaicism in the mother

K Michalová, F Kloucek, J Musilová

Deletion of 13q in two patients with retinoblastoma, one probably due to 13q-mosaicism in the mother

K Michalová et al. Hum Genet. 1982.

Abstract

We examined the peripheral blood chromosomes of eight patients with retinoblastoma. In two of them an interstitial deletion of 13q was found. The breakpoints were determined as follows: case 1, 13q12 leads to 21; case 2 13q12 leads to 31. In both cases, band 13q14 was deleted. In case 2 the lymphocytes of the mother showed the identical interstitial 13q deletion in 3 of 100 mitoses, thus raising the possibility of maternal origin of the 13q deletion in a child. In one patient, retinoblastoma was unilateral; in the other, bilateral. Both patients were mentally retarded.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Chromosoma. 1978 Aug 14;67(4):293-307 - PubMed
    1. Ann Genet. 1979 Jun;22(2):106-7 - PubMed
    1. Science. 1980 May 30;208(4447):1042-4 - PubMed
    1. Hum Genet. 1980;56(1):53-8 - PubMed
    1. Hum Genet. 1976 Oct 28;34(2):199-206 - PubMed

LinkOut - more resources