An improved procedure for the determination of ethylene glycol in blood
- PMID: 7176557
- DOI: 10.1093/jat/6.5.253
An improved procedure for the determination of ethylene glycol in blood
Abstract
A method is presented for the analysis of ethylene glycol in whole blood by GC/FID using 1,2-butanediol as the internal standard (IS). The diols are derivatized during extraction from whole blood using n-butylboronic acid and then extracted as pseudo weak acids prior to analysis. As little as 10 mg/L of ethylene glycol in blood can be detected by this method.
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