Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1982 Jan-Mar;1(1):73-82.
doi: 10.1002/sim.4780010110.

The design of a sequential clinical trial for the comparison of two lung cancer treatments

D R Jones, C E Newman, J Whitehead
Comparative Study

The design of a sequential clinical trial for the comparison of two lung cancer treatments

D R Jones et al. Stat Med. 1982 Jan-Mar.

Abstract

The steps in designing a controlled trial to evaluate a new treatment for inoperable carcinoma of the bronchus are described. The principal outcome measure is survival time from treatment allocation, and the duration of the trial is determined by application of the sequential logrank test. The detailed determination of the stopping rule and the arrangements for analyses are described.

PubMed Disclaimer

Publication types

LinkOut - more resources