Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Jan;16(1):77-86.
doi: 10.1007/BF02618201.

The analysis of malignancy by cell fusion

E Sidebottom

The analysis of malignancy by cell fusion

E Sidebottom. In Vitro. 1980 Jan.

Abstract

The lecture reviews some aspects of the work on the analysis of malignancy that have been, and are now being, pursured in the Dunn School. A brief outline of the early experiments that first demonstrated that the malignancy of mouse tumor cells can be suppressed by the fusion with normal cells is given, and then two areas of current interest in the laboratory are described. The first is an attempt to analyze the clinically important property of tumors to metastasize and the second is the work on the isolation and identification of an abnormal membrane glycoprotein present in tumor cells. In addition the value of cell fusion methods as a general test of hypotheses of malignancy is emphasized.

PubMed Disclaimer

References

    1. Methods Cell Biol. 1973;7:157-88 - PubMed
    1. J Biol Chem. 1977 Jun 10;252(11):3926-33 - PubMed
    1. Proc Natl Acad Sci U S A. 1975 Sep;72(9):3323-7 - PubMed
    1. Biochemistry. 1971 Mar 30;10(7):1143-8 - PubMed
    1. Proc R Soc Lond B Biol Sci. 1978 Apr 13;201(1142):87-106 - PubMed

Publication types

MeSH terms