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. 1980 Apr;17(2):136-8.
doi: 10.1136/jmg.17.2.136.

Monozygotic twins discordant for Wiedemann-Beckwith syndrome and the implications for genetic counselling

A C Berry, E M Belton, C Chantler

Monozygotic twins discordant for Wiedemann-Beckwith syndrome and the implications for genetic counselling

A C Berry et al. J Med Genet. 1980 Apr.

Abstract

A pair of monozygous twins discordant for Wiedemann-Beckwith syndrome is described and published reports reviewed to establish the mode of inheritance. Single gene control seems unlikely and it is proposed that the condition arises from the interaction of "at risk" genes in the fetus and metabolic factors in the mother, which suggests multifactorial control.

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