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. 1981 Apr;31(4):371-6.
doi: 10.1212/wnl.31.4.371.

Lisuride in parkinsonism

G Gopinathan, H Teräväinen, J M Dambrosia, C D Ward, J N Sanes, W K Stuart, E V Evarts, D B Calne

Lisuride in parkinsonism

G Gopinathan et al. Neurology. 1981 Apr.

Abstract

We studied the actions of lisuride, a dopaminergic ergot derivative, in 20 parkinsonian patients. When the dose was increased gradually, most patients tolerated up to 5 mg daily. Clinical assessment and objective, computer-assisted evaluation revealed improvement in akinesia, rigidity and tremor. Adverse reactions were similar to those seen with levodopa and bromocriptine, but somnolence tended to occur more often with lisuride.

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