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. 1981;17(5):940-2.

[Characteristics of an interspecies somatic hybrid (Chinese hamster X mouse)]

[Article in Russian]
N V Pankova, T M Seregina, M I Mekshenkov
  • PMID: 7195857

[Characteristics of an interspecies somatic hybrid (Chinese hamster X mouse)]

[Article in Russian]
N V Pankova et al. Genetika. 1981.

Abstract

An interspecific somatic hybrid between the biochemically marked cell lines of Chinese hamster (M-15-1) and mouse (B-82) was obtained. Morphology of the hybrid, its karyotype characteristics in the 9-th and 22-nd passages, as well as kinetics of growth were studied. Periods of doubling of the hybrid cells, the Chinese hamster M-15-1 cells and the mouse B-82 cells proved to be 26, 18 and 21 h, respectively. It was revealed, that elimination of chromosomes took place in the course of the hybrid cells reproduction at the expense of two-arm chromosomes of both parental lines.

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