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. 1981 Jun:49:299-310.
doi: 10.1242/jcs.49.1.299.

The effects of fibronectin on the adhesion and migration of chinese hamster ovary cells on collagen substrata

S L Schor, A M Schor, G W Bazill

The effects of fibronectin on the adhesion and migration of chinese hamster ovary cells on collagen substrata

S L Schor et al. J Cell Sci. 1981 Jun.

Abstract

Data are presented indicating that the adhesion of Chinese hamster ovary cells (CHO) to films of denatured type I collagen occurs by a fibronectin-dependent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism. Data are also presented indicating that fibronectin promotes the migration of CHO cells on native type I collagen fibres.

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