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. 1978 Dec 1;90(2):101-6.
doi: 10.1016/0009-8981(78)90510-7.

Study of influence of sex and age on human serum lysosomal enzymes by using 4-methylumbelliferyl substrates

P Annunziata, G Dimatteo

Study of influence of sex and age on human serum lysosomal enzymes by using 4-methylumbelliferyl substrates

P Annunziata et al. Clin Chim Acta. .

Abstract

The sex and age dependence of activity of eight glycosidases and acid phosphatase was assayed in serum samples using the 4-methylumbelliferyl substrates. The activity of these enzymes does not change in relation to sex and to age except for acid phosphatase and beta-galactosidase which show significantly higher values in children as compared to adults. The usefulness of the 4-MU substrates for the detection of homozygotes for those lysosomal diseases involving one of the glycosidases studied is discussed.

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