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Case Reports
. 1982 Mar 1;49(5):999-1004.
doi: 10.1002/1097-0142(19820301)49:5<999::aid-cncr2820490525>3.0.co;2-3.

Neurotropic melanoma of the vulva

T F Warner, G R Hafez, D A Buchler
Case Reports

Neurotropic melanoma of the vulva

T F Warner et al. Cancer. .

Abstract

A spindle cell melanoma of the clitoris was associated with a large area of lentiginous melanocytic dysplasia in the vulva of a 51-year-old woman. There was extensive neoplastic of the dermis, a desmoplastic reaction, and replacement of perineurial and Schwann cells by tumor cells (neurotropism). The superficial dysplastic components were pigmented, but melanosomes were not identified in a lymph node metastasis. Here the internuclear areas strongly resembled neuropil. Vulvar melanoma is rate, and this is the first report of neurotropic melanoma in this site.

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