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. 1980 Nov 21;68(2):201-4.
doi: 10.1016/0014-2999(80)90323-4.

The hypotensive effect of centrally administered tyrosine

The hypotensive effect of centrally administered tyrosine

Y Yamori et al. Eur J Pharmacol. .

Abstract

Intraventricular injection of 15 microgram L-tyrosine results in a significant reduction in blood pressure in the spontaneously hypertensive rat. An increase in the turnover of norepinephrine as indexed by MOPEG-SO4 is observed concurrently. The data are consistent with the previously suggested depressor role of certain central noradrenergic neurons.

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