Action of GABA and glycine on the membrane potential of culture astrocytes and the extracellular concentration
- PMID: 7202647
- DOI: 10.1007/BF01960118
Action of GABA and glycine on the membrane potential of culture astrocytes and the extracellular concentration
Abstract
The depolarization of cultured astrocytes by GABA and glycine correlates in amplitude and time course with the increase of the extracellular K+ -concentration during perfusion with these amino acids. It is suggested that the glial depolarization is caused by an efflux of K+ from neighbouring neurones activated by the amino acid transmitters.
Similar articles
-
Evidence that the depolarization of glial cells by inhibitory amino acids is caused by an efflux of K+ from neurones.Exp Brain Res. 1981;42(1):43-8. doi: 10.1007/BF00235727. Exp Brain Res. 1981. PMID: 7215508
-
Aspartate, glutamate and gamma-aminobutyric acid depolarize cultured astrocytes.Neurosci Lett. 1984 Nov 23;52(1-2):25-9. doi: 10.1016/0304-3940(84)90345-8. Neurosci Lett. 1984. PMID: 6152041
-
86Rubidium release from cultured primary astrocytes: effects of excitatory and inhibitory amino acids.Neuroscience. 1989;30(1):223-9. doi: 10.1016/0306-4522(89)90367-9. Neuroscience. 1989. PMID: 2568601
-
Actions of gamma-aminobutyric acid on rat supraoptic nucleus neurosecretory neurones in vitro.J Physiol. 1987 Jun;387:629-47. doi: 10.1113/jphysiol.1987.sp016592. J Physiol. 1987. PMID: 3656185 Free PMC article.
-
Excitatory amino acids directly depolarize rat brain astrocytes in primary culture.Nature. 1984 Oct 18-24;311(5987):656-9. doi: 10.1038/311656a0. Nature. 1984. PMID: 6148706
References
MeSH terms
Substances
LinkOut - more resources
Medical