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Case Reports
. 1980;55(3):309-14.
doi: 10.1007/BF00290209.

H-Y antigen expression in a case of XX true hermaphroditism

C A Moreira-Filho, P G Otto, Z Mustacchi, O Frota-Pessoa, P A Otto
Case Reports

H-Y antigen expression in a case of XX true hermaphroditism

C A Moreira-Filho et al. Hum Genet. 1980.

Abstract

Cells from an XX true hermaphrodite expressed a reduced amount of H-Y antigen when compared with normal XY cells and with cells from his father, who had an XY/XX chromosomal constitution. His mother had a normal karyotype and was H-Y negative. The four brothers of the patient were clinically and karyotypically normal. An X-Y interchange followed by random inactivation of the X chromosome is proposed to explain the H-Y antigen titer found in the patient.

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