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. 1980;55(3):333-6.
doi: 10.1007/BF00290213.

Effects of temperature on sister chromatid exchanges

G Speit

Effects of temperature on sister chromatid exchanges

G Speit. Hum Genet. 1980.

Abstract

The influence of temperature on sister chromatid exchanges was investigated, and the results are discussed in connection with factors possible involved in temperature-induced SCE-formation. Whereas the SCE frequency increased with increasing growth temperature in a cell line of Xenopus laevis (EAX), which permits the examination of great temperature differences, a Chinese hamster cell line (V-79) revealed a U-shaped temperature-response curve. In addition, it was found that cold treatment at 4 degrees C caused an induction of SCEs in the V-79 cell line. Different BrdU concentrations had no effect on the temperature-induced SCE frequencies and mitomycin C led to an induction of SCEs parallel to the base-line values at different temperatures.

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References

    1. Science. 1965 May 21;148(3673):1092-4 - PubMed
    1. Mycopathologia. 1976 Dec 10;60(1):51-6 - PubMed
    1. Nature. 1980 Mar 6;284(5751):74-6 - PubMed
    1. Mutat Res. 1978 Sep;51(3):411-8 - PubMed
    1. Exp Cell Res. 1965 Aug;39(1):103-16 - PubMed