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. 1981;50(1):29-37.
doi: 10.1007/BF01254911.

Effect of choline on central dopaminergic function in normal subjects

S Lal, P Etienne, J Thavundayil, N P Nair, B Collier, R Rastogi, H Guyda, G Schwartz

Effect of choline on central dopaminergic function in normal subjects

S Lal et al. J Neural Transm. 1981.

Abstract

Oral administration of choline (10 g) had no effect on basal serum growth hormone or prolactin concentrations in normal subjects (N = 5). Choline significantly enhanced the increase in growth hormone secretion induced by apomorphine HCl (0.5 mg s.c.). These data suggest that cholinergic mechanisms may enhance hypothalamic-pituitary dopaminergic function in man in contrast to their inhibitory effect on dopaminergic function in the basal ganglia.

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