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. 1978 Oct;4(2):167-74.
doi: 10.1016/0378-1119(78)90028-8.

Least-squares method for restriction mapping

Least-squares method for restriction mapping

J L Schroeder et al. Gene. 1978 Oct.

Abstract

A least-squares procedure has been developed to aid in deriving restriction-fragment maps once the order of cutsites has been determined. A computer program which carries out this method can be used to map either linear or circular molecules.

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