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. 1980 Nov;58(11):1241-6.

[Carbon 13 nuclear magnetic resonance conformation studies of peptides with analgesic activity]

[Article in French]
R R Smolders, R Coomans, F Jacquemotte, Y Van Haverbeke, A Maquestiau, R Muller
  • PMID: 7214191

[Carbon 13 nuclear magnetic resonance conformation studies of peptides with analgesic activity]

[Article in French]
R R Smolders et al. Can J Biochem. 1980 Nov.

Abstract

13C Nuclear magnetic resonance studies of proline peptides with central antalgic activity (Pro-Arg, Arg-Pro, Pro-Arg-Pro, Pro-Lys-Pro) indicate a predominance of trans conformation at all pH values; but their physiological activities appear to be related to the ability of the C-terminal proline peptides to assume the cis conformation.

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