Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981 Feb;31(2):775-82.
doi: 10.1128/iai.31.2.775-782.1981.

Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis

D A Portnoy, S L Moseley, S Falkow

Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis

D A Portnoy et al. Infect Immun. 1981 Feb.

Abstract

Yersinia enterocolitica isolates harboring a particular species of plasmid deoxyribonucleic acid showed a high degree of lethality for gerbils and caused the detachment of HEp-2 tissue cell monolayers. Strains cured of their plasmid deoxyribonucleic acid showed loss of these properties. However, invasiveness of HEp-2 cells was shown not to be a plasmid-mediated property. The expression of plasmid-associated properties, including at least three major outer membrane polypeptides, occurred during growth at 37 but not at 25 degrees C and was related to the concentration of calcium in the growth medium. The plasmid species associated with these properties ranged in molecular mass from 40 x 10(6) to 48 x 10(6) daltons and comprised a family of related plasmids.

PubMed Disclaimer

References

    1. Biochem Biophys Res Commun. 1966 Jun 13;23(5):641-6 - PubMed
    1. J Bacteriol. 1979 Sep;139(3):792-9 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. J Bacteriol. 1969 May;98(2):637-50 - PubMed
    1. Infect Immun. 1980 May;28(2):638-40 - PubMed

Publication types

LinkOut - more resources