New antibiotics from the fungus Epicoccum nigrum. I. Fermentation, isolation and antibacterial properties
- PMID: 721706
- DOI: 10.7164/antibiotics.31.1099
New antibiotics from the fungus Epicoccum nigrum. I. Fermentation, isolation and antibacterial properties
Abstract
An atmosphere isolate of the fungus Epicoccum nigrum was found to exhibit an activity against Staphylococcus aureus. A more active, non-sporulating variant of this strain was selected. From its fermentation broth, two novel compounds, epicorazines A and B, were isolated by preparative TLC and tested against a series of bacteria.
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