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Comparative Study
. 1981 May;126(5):2011-4.

Natural cytotoxic cells against solid tumors in mice. III. A comparison of effector cell antigenic phenotype and target cell recognition structures with those of NK cells

E C Lattime, G A Pecoraro, O Stutman
  • PMID: 7217680
Comparative Study

Natural cytotoxic cells against solid tumors in mice. III. A comparison of effector cell antigenic phenotype and target cell recognition structures with those of NK cells

E C Lattime et al. J Immunol. 1981 May.

Abstract

Antisera directed to antigens present on natural killer (NK) cells such as Qa-2,3, Qa-5, NK-1.2, Ly 11.2, and Asialo GM 1 failed to eliminate natural cytotoxic (NC) cell activity from murine spleen cells, suggesting a heterogeneity of effector populations involved in natural cell-mediated cytotoxicity (NCMC). Cross-cold target inhibition studies demonstrated that certain similar recognition structures are present both on NK and NC susceptible tumor target cells.

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