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. 1981 Jan-Feb;5(1):6-9.
doi: 10.1093/jat/5.1.6.

Organochlorine pesticides in specimens from women undergoing spontaneous abortion, premature of full-term delivery

M C Saxena, M K Siddiqui, T D Seth, C R Krishna Murti, A K Bhargava, D Kutty

Organochlorine pesticides in specimens from women undergoing spontaneous abortion, premature of full-term delivery

M C Saxena et al. J Anal Toxicol. 1981 Jan-Feb.

Abstract

Organochlorine insecticides (BHC, aldrin, p,p'-DDE, p,p'-DDD, p,p'-DDT) were measured in the blood, placenta and fetus of women experiencing spontaneous abortions, preterm labor or full-term labor using an electron-capture gas chromatographic method. The following trend was found for insecticide concentrations in each of the specimens tested: spontaneous abortions greater than preterm greater than full-term. One conclusion of this work is that the organochlorine insecticides act as antagonists to pregnancy. A plausible explanation for the facilitory role of organochlorine insecticides in the initiation of preterm labor/abortion is hypothesized.

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