More data on mercury absorption in relation to dietary treatment in rats

Abstract

The kinetics of mercury (Hg) absorption in relation to diet by determining whole body (WB), carcass (C) and gut (G) retention in control and milk-fed rats 6, 9, 12 and 15 days after oral administration of 203Hg have been studied. All retention values were higher in the milk-fed than in control rats during the experimental period. The higher WB retention in the milk-fed animals was primarily due to increased G retention especially at shorter time intervals. Animals on the milk diet had in the C, higher retention values, and in the G, higher retention and longer residence time. There was no evidence that Hg from the gut compartment entered into other parts of the body within the observation period. More evidence is needed about the effect of other dietary treatments on Hg metabolism.