On the morphogenesis of ulegyria

Abstract

An 11 day old premature infant survived 8 days after a cardiac arrest. At necropsy, the infant's brain showed cortical arteries surrounded by cuffs of viable neurones, while the cortex between these arteries was necrotic. This appearance suggests that the pattern of nodules of neurones separated by radial bands of scar seen in ulegyria is probably the result of healing of similar cortical infarcts, which are oligemic intracortical boundary zone infarcts occurring when the arterial vascular bed is immature.