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. 1980 Nov;27(6):576-7.
doi: 10.1007/BF03006890.

[Accidental overdose of alfatesine in a child with multiple malformations]

[Article in French]
G Boulard, G Miet, J Guerin, M Sabathie

[Accidental overdose of alfatesine in a child with multiple malformations]

[Article in French]
G Boulard et al. Can Anaesth Soc J. 1980 Nov.

Abstract

An overdosage of alfathesin was accidentally administered to a 4 kg infant with multiple congenital anomalies during an operation for craniosynostosis. The overdose was a consequence of a mistake in adjusting the rate of administration of a constant flow infusion pump. The total dosage corresponded to eight times the necessary dose administered over a period of 30 minutes. The only notable effect was a delayed awakening, which necessitated assisted ventilation. The high therapeutic index of alfathesin is responsible for the absence of serious consequences.

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References

    1. Ann Anesthesiol Fr. 1980;21(5):506-10 - PubMed
    1. Can Anaesth Soc J. 1978 May;25(3):245-6 - PubMed

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