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. 1980;1(6):355-60.
doi: 10.1016/0166-0934(80)90053-1.

A sensitive plaque inhibition technique for assay of antibodies to influenza virus: use to detect previous antigenic priming with influenza viruses

Z Zakay-Rones, E Margalith, R Levy, E Katz

A sensitive plaque inhibition technique for assay of antibodies to influenza virus: use to detect previous antigenic priming with influenza viruses

Z Zakay-Rones et al. J Virol Methods. 1980.

Abstract

Plaque reduction test performed in MDCK cells was found to be a more sensitive assay than hemagglutination inhibition, for revealing previous immunological experience with influenza A virus in the population. Based on the preimmunization antibody levels, determined by plaque reduction tests, it was possible to distinguish between previously primed and unprimed subjects among vaccinees.

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