Molecular cloning and characterization of cDNA sequences coding for rat relaxin
- PMID: 7231533
- DOI: 10.1038/291127a0
Molecular cloning and characterization of cDNA sequences coding for rat relaxin
Abstract
Using a synthetic oligonucleotide primer, cloned DNA fragments, each containing the entire coding sequence of rat relaxin, have been isolated from a clone 'bank' of ovarian mRNA sequences. The nucleotide sequence of these clones demonstrates that relaxin is synthesized as a preprorelaxin molecule with an unexpectedly large connecting peptide of 105 amino acid residues.
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