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. 1981 Jun 15;214(2):429-32.
doi: 10.1016/0006-8993(81)91207-5.

A transient increase in junctional acetylcholine receptors after denervation

A transient increase in junctional acetylcholine receptors after denervation

A Olek et al. Brain Res. .

Abstract

An improved method for assaying acetylcholine (ACh) receptors at the neuromuscular junction has been used to examine the effects of denervation in the rat diaphragm. An early increase of junctional ACh receptors occurred after two days of denervation followed by a decline at 14 days. Possible mechanisms responsible for this transient increase in junctional ACh receptors are discussed.

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