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Case Reports
. 1981 May;28(3):280-2.
doi: 10.1007/BF03005516.

Excessive requirement for heparin during cardiac surgery

F Chung, T E David, J Watt
Case Reports

Excessive requirement for heparin during cardiac surgery

F Chung et al. Can Anaesth Soc J. 1981 May.

Abstract

A case of excessive heparin requirement during cardiopulmonary bypass is reported. A patient with sepsis secondary to a myocardial abscess require 13.5 mg x kg-1 of heparin to increase his activated coagulation time to a therapeutic level. This phenomenon might be due to individual variability, lupus vasculitis, septicaemia, repeated thromboembolic phenomenon with hypercoagulable state, or chronic disseminated intravascular coagulation with partial antithrombin deficiency.

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