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. 1981 Apr;26(4):325-7.
doi: 10.1007/BF01308373.

Hepatic morphology in obesity

S M Nasrallah, C E Wills Jr, J T Galambos

Hepatic morphology in obesity

S M Nasrallah et al. Dig Dis Sci. 1981 Apr.

Abstract

Changes in hepatic morphology were evaluated in 242 consecutive liver biopsy specimens obtained from nonalcoholic obese subjects. Steatosis occurred in 59.7% of the subjects but was moderate to severe in 28.7%. An alcoholic hepatitis-like picture was present in 8.7% and cirrhosis in 2.7%. Fibrosis of mild and moderate degrees was encountered in 26.1% and 5.8%, respectively. This study indicates that the histopathological changes that occur in the livers of obese subjects are similar to alcoholic liver injury.

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