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. 1978 Nov 30;276(5687):471-4.
doi: 10.1038/276471a0.

Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound

A H Wang, J Nathans, G van der Marel, J H van Boom, A Rich

Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound

A H Wang et al. Nature. .

Abstract

The crystal structure of a complex containing deoxy CpG and a terpyridine platinum compound (TPH) shows a DNA double helical fragment with TPH intercalated between two Watson-Crick GC base pairs. The DNA unwinding angle is 23 degrees and the pucker of the deoxyribose rings differ at the 3' and 5' ends.

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