[Pressure-volume ratio in the craniospinal cavity in supra- and subtentorial pathology. I. Changes in cerebrospinal fluid pressure in cerebrospinal fluid compression and decompression of the brain]

Abstract

The p-V dependence in the craniospinal cavity was studied by the method of dosaged change in the cerebrospinal fluid volume in 15 neurooncological patients who underwent operation for tumor of the posterior cranial fossa in the chiasmal-sellar area. It is shown that this dependence, reflecting the biophysical properties of the intracranial system, has distinguishing features in patients with supra- and subtentorial pathology. For instance, in FP values close to zero the resilience of the intracranial system is higher in patients with supratentorial processes than in patients with subtentorial pathology. In artificial c.s.f. compression, intracranial system resilience grows gradually in patients with basal pathology and increases much more rapidly in patients with subtentorial pathology. The authors discuss the possible causes of the difference in P-V dependence in the groups of patients who were examined and the significance of the obtained information in substantiating intensive therapy in the immediate postoperative period.