[Inhibitory analysis of the luminescent electron transport chain of Photobacterium fischeri]
- PMID: 7248374
[Inhibitory analysis of the luminescent electron transport chain of Photobacterium fischeri]
Abstract
The quenching of luminescence of bacterial luciferase from Photobacterium fischeri by non-specific electron acceptors and inhibitors of dehydrogenases was studied. The inhibition of the luminescent reaction obeys the non-competitive mechanism with NADH, FMN and aliphatic aldehyde. The inhibitors compete with cytochrome c for NADH -- cytochrome c oxido-reductase. It is concluded that lumiredoxin, a FeS-containing protein, is the most sensitive component of the luminescent electron transport chain.
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