The long term safety of hormonal steroid contraceptives
- PMID: 7249946
- DOI: 10.2165/00003495-198121060-00005
The long term safety of hormonal steroid contraceptives
Abstract
PIP: The accumulated data on combined OC (oral contraceptive) use makes it possible to assess with accuracy the longterm risk associated with such use. The risks for young women are low. Risks rise with age and such factors as smoking, hypertension, diabetes, and hyperlipidemia. Women over 35, especially smokers, are at considerable risk of vascular disease. There are small risks of liver, endometrial, and cervical neoplasms, increasing with use and other risk factors. Diabetes may be accelerated. There is also a risk of depression in susceptible patients. For oral and injectable progestagen-only contraceptives, the risks are reasonably well documented in the short- but not the longterm. With progestagen-only minipills, the risks other than that of pregnancy are low. Injectable progestagen may cause anaphylaxis at the time of injection.
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