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. 1977 Nov;68(5 Suppl):679-87.

Oncofetal antigens. Increasing the specificity of the CEA radioimmunoassay

  • PMID: 72501

Oncofetal antigens. Increasing the specificity of the CEA radioimmunoassay

J Shuster et al. Am J Clin Pathol. 1977 Nov.

Abstract

The biologic and clinical significance of the oncofetal antigens carcinoembryonic antigen (CEA) and alpha1-fetoprotein (AFP) are discussed. Although the current assays for these molecules are not tumor-specific, measurement of these molecules in the circulation of cancer patients is useful either for tumor diagnosis or for management of the cancer patient in the postoperative or post-chemotherapy state. An approach to increasing the specificity of the CEA radioimmunoassay is described.

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