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. 1981 May 15;37(5):496-7.
doi: 10.1007/BF01986159.

Inhibitory action of bradykinin on release of the adrenergic transmitter in the isolated lapine kidney

K U Malik, A Nasjletti

Inhibitory action of bradykinin on release of the adrenergic transmitter in the isolated lapine kidney

K U Malik et al. Experientia. .

Abstract

In the isolated lapine kidney perfused with tyrode solution and prelabeled with [3H] norepinephrine, bradykinin (10 ng/ml) decreased the overflow of tritium elicited by sympathetic nerve stimulation both in the presence and absence of indomethacin. These observations indicate that bradykinin acts at presynaptic sites reducing release of the adrenergic transmitter in the isolated lapine kidney.

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