Chemical-enzymatic synthesis of biologically active DNA fragments
- PMID: 7255175
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Chemical-enzymatic synthesis of biologically active DNA fragments
Nucleic Acids Symp Ser.
1980.
Abstract
In this communication we report our recent investigations concerned the design and construction of synthetic functionally active DNA fragments: the structural gene for pentapeptide Leu-enkephalin and the double-stranded 93 base pairs long polynucleotide representing the promoter region of bacteriophage fd DNA. The ways for synthesis of modified promoter analogs carrying photosensitive residues of 5-bromodeoxyuridine in different positions of the chain are also considered.
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