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. 1977 Dec 1;471(2):189-94.
doi: 10.1016/0005-2736(77)90249-8.

Single channel characteristics of some synthetic gramicidins

R H Tredgold, P N Hole, R C Sproule, M Elgamal

Single channel characteristics of some synthetic gramicidins

R H Tredgold et al. Biochim Biophys Acta. .

Abstract

The synthesis of two new variants of gramicidin is described. It is shown that the changes in the aromatic side groups do not influence the single channel conductivity. Experiments in which solutions having different molarities on the two sides of the bilayer lipid membrane are described and their results compared with a rate theory analysis. It is concluded that the gramicidin pore contains approximately 10 equal potential maxima.

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