[Combined surgical and specific passive xenogenic immunotherapy in UVT tumor-bearing inbred XVII/Bln mice]

Abstract

The influence of surgical tumor exstirpation and application of 9,6 x 10(6) sensitized rabbit lymphocytes in inbreeding mice was compared with unique surgical therapy. No therapeutic result existed with unique immunotherapy and advanced growth of the tumor (Winzer and Wolf). 74% of the mice were alive with combined therapy on the 21st day after operation respectively on the 31st day after transplantation. On the other hand only 53% of the mice were alive with surgical therapy alone. A clinical use of a unique passive xenogenous immunotherapy does not appear to be indicated, because there was not reached a constant remission.