Platelet monoamine oxidase and epinephrine-induced platelet aggregation
- PMID: 725849
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Platelet monoamine oxidase and epinephrine-induced platelet aggregation
Thromb Haemost.
.
Abstract
Platelet MAO activity and the aggregation response to epinephrine, ADP, and collagen were measured in normal subjects. There was a direct correlation between the amount of platelet MAO activity and the per cent aggregation induced by 1 and 2 micrometer epinephrine. There were lesser correlations between platelet MAO and ADP or collagen-induced aggregation. These findings suggest that platelet MAO may play a role in determining the response of human platelets to epinephrine.
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