Reduction of polymeric azo and nitro dyes by intestinal bacteria
- PMID: 7259159
- PMCID: PMC243905
- DOI: 10.1128/aem.41.5.1283-1286.1981
Reduction of polymeric azo and nitro dyes by intestinal bacteria
Abstract
The O(2)-sensitive reduction of high-molecular-weight aromatic azo and nitro dyes by intestinal bacteria appears to be mediated by low-molecular-weight electron carriers with E(o)' = -200 to -350 mV. This process may allow the design of polymeric azo prodrugs for specific release of certain aromatic amines in the colon.
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