Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Apr;30(1):181-6.
doi: 10.1016/S0006-3495(80)85086-7.

Intracellular Na+ activity as a function of Na+ transport rate across a tight epithelium

N K Wills, S A Lewis

Intracellular Na+ activity as a function of Na+ transport rate across a tight epithelium

N K Wills et al. Biophys J. 1980 Apr.

Abstract

Liquid Na+ resin microelectrodes were used to measure intracellular Na+ activities (alpha iNa+) in the mammalian tight epithelium, rabbit urinary bladder. alpha iNa+ averaged 7 +/- 1 mM and was independent of Na+ transport rate over the range of 2 to 8 muA/muF. (1 mF congruent to 1 cm2 apical membrane area). After Na+ loading the cells the Na+ pump in the basolateral membrane was measurably electrogenic. A method for shielding the Na+-sensitive microelectrodes is described which increases the response time and eliminates an electrical shunting artifact.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Membr Biol. 1976 AUG 27;28(1):1-40 - PubMed
    1. J Membr Biol. 1976 AUG 27;28(1):41-70 - PubMed
    1. J Membr Biol. 1978 Jun 28;41(2):117-48 - PubMed
    1. Science. 1979 Mar 30;203(4387):1349-51 - PubMed

Publication types

LinkOut - more resources