On the energy dissipation in a tank-treading human red blood cell

Abstract

The energy dissipation in the membrane (ED mem) and in the cytoplasm (ED cyt) of tank-treading human red blood cells is estimated. The tank-tread motion of the membrane occurs when the cells in a sheared suspension assume a steady-state of orientation (Fischer et al., 1978, Science [Wash. D. C.], 202:894). The kinematic data used are from red cells suspended either in a dextran-saline solution at a low hematocrit, or in plasma at a hematocrit of 45%. The viscosities of the cytoplasm and the membrane are taken from the literature. The cell in dextran was subjected to seven different shear rates. Both ED mem and ED cyt showed a strong increase with shear rate. Their ratio, however, was always of the order of 1. From this value and the value which was given by Hochmuth et al. (1979, Biophys. J., 26:101) for a shape recovery of a red cell, it is concluded that the range of ED mem/ED cyt for all possible geometries is 1-100.