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. 1981 Jun;227(3):415-7.
doi: 10.1016/0165-3806(81)90078-x.

The maturation of cortical serotonin binding sites

The maturation of cortical serotonin binding sites

L L Uphouse et al. Brain Res. 1981 Jun.

Abstract

Binding of serotonin to rat brain membranes increased linearly from birth to adulthood, but newborn receptor densities were already 39% of adult levels. These data suggest a postnatal development of serotonin receptors, coincident with synaptic maturation but do not preclude a non-transmitter function for serotonin during early maturation.

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