Hormones and mouse mammary tumorigenesis

Abstract

The hormonal milieu of the host influences viral and chemical carcinogen-induced mammary tumorigenesis in a variety of indirect ways. The effects of a high-fat diet on mouse mammary tumorigenesis are very limited and are convincing only for ice infected by the high-oncogenic mammary tumor virus. The relationship between fat content in the diet, the hormonal milieu of the host, and mammary tumor virus function is unexplored.