[Retinoid therapy and phototherapy of psoriasis (author's transl)]

Abstract

26 patients with generalized psoriasis were treated with oral Retinoid (Ro 10-9359; 50-150 mg/day) and radiations (2-5 times per week) with two different light sources emitting UVA and UVB. In 22 patients, remission was seen with only few remaining lesions at the predilection sites within 35 days. There was no obvious difference in the effect of the two light sources. 17 patients remained free from lesions for several months under a low-dose treatment with Ro 10-9359 and 2-8 radiations per month. The side effects of this treatment were negligible. This therapy is especially suited for outdoor patients with generalized psoriasis.