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. 1980 Dec;96(4):967-74.
doi: 10.1093/genetics/96.4.967.

Lack of genic variation in the abundant proteins of human kidney

S C Smith, R R Racine, C H Langley

Lack of genic variation in the abundant proteins of human kidney

S C Smith et al. Genetics. 1980 Dec.

Abstract

Abundant proteins of 25 human kidneys were surveyed for genic variation by means of two-dimensional electrophoresis. Eighty-three (83) proteins were scored, and no genic variation was detected. This reduction in genic heterozygosity corroborates results determined with two-dimensional electrophoresis in mice and flies. These results suggest that previous estimates of electrophoretic variation may have been in error because of biased selection of loci.

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