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Case Reports
. 1980 Dec;56(662):877-8.
doi: 10.1136/pgmj.56.662.877.

Black urine

P Altmann, M A Mansell
Case Reports

Black urine

P Altmann et al. Postgrad Med J. 1980 Dec.

Abstract

A patient is described in whom spontaneous blackening of the urine, due to melanin formation, resulted from treatment with alpha-methyldopa. The colour change became apparent only after the correction of a severe postoperative hyponatraemic alkalosis, the urinary pH had become alkaline, as melanin formation in acid urine is very slow.

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References

    1. JAMA. 1966 Apr 18;196(3):286-8 - PubMed
    1. Lancet. 1969 Aug 9;2(7615):326 - PubMed
    1. N Engl J Med. 1974 Nov 21;291(21):1142 - PubMed
    1. Kidney Int. 1976 Jul;10(1):104-16 - PubMed
    1. J Pharmacol Exp Ther. 1964 Feb;143:205-14 - PubMed

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