Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Oct 15;176(1):335-8.
doi: 10.1042/bj1760335.

Evidence for the participation of aspartate aminotransferase in hepatic glucose synthesis in the suckling newborn rat

P Ferré, D H Williamson

Evidence for the participation of aspartate aminotransferase in hepatic glucose synthesis in the suckling newborn rat

P Ferré et al. Biochem J. .

Abstract

Inhibition of liver aspartate aminotransferase by L-2-amino-4-methoxy-trans-3-butenoic acid in the suckling newborn rat causes a decrease in all gluconeogenic precursors from phosphoenolpyruvate to glucose and an accumulation of lactate but not of pyruvate. This suggests that the aspartate shuttle is operative and confirms the quantitative importance of lactate as a gluconeogenic precursor at this time during development.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Biochem Z. 1959;332:18-46 - PubMed
    1. Biochim Biophys Acta. 1967 Jan 11;132(1):175-8 - PubMed
    1. Biochem J. 1962 Jan;82:90-6 - PubMed
    1. Biochem J. 1977 Feb 15;162(2):453-5 - PubMed
    1. Biochem J. 1977 Sep 15;166(3):631-4 - PubMed