Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1981 Aug;10(2):122-6.
doi: 10.1002/ana.410100203.

Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis

P J Whitehouse, D L Price, A W Clark, J T Coyle, M R DeLong
Case Reports

Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis

P J Whitehouse et al. Ann Neurol. 1981 Aug.

Abstract

The nucleus basalis of Meynert provides diffuse cholinergic input to the neocortex. When compared with an age- and sex-matched control, the nucleus basalis from a patient with Alzheimer disease demonstrated substantial reduction of neurons. Loss of this neuronal population may represent an anatomical correlate of the well-documented cholinergic derangement in Alzheimer disease.

PubMed Disclaimer

Publication types

LinkOut - more resources